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Cafergot is a combination medication containing ergotamine and caffeine which is used to treat certain types of headaches including cluster and migraine headaches. Headache pain is sometimes caused by widened blood vessels in the head. Ergotamine works to narrow widened blood vessels while caffeine increases the absorption of ergotamine while also narrowing blood vessels.

Make sure to always read the patient information and instructions before using this medication. Always follow your doctor’s directions.

• Cafergot should be taken with or without food at the first sign of a headache. A typical dose is two tablets initially followed by another tablet every thirty minutes until the headache is relieved.
• Do not take more than six tablets for one headache or ten tablets during a seven-day period.
• Cafergot is most effective when it is taken at the first sign of a headache. It may not be as effective if taken once a headache has worsened.
• Cafergot should only be taken as needed and is not meant for long-term daily use.
• If you are taking migraine medication for more than ten days each month, your headaches may actually get worse due to medication overuse headache.

Tell your doctor and pharmacist:

• About your drug and other allergies.
• If you take any other prescription or over-the-counter medications.
• Your medical history particularly of blood circulation problems, headaches, heart problems, kidney disease, liver disease, stroke, “mini-stroke”, high blood pressure, high cholesterol or diabetes.
• If you have a personal or family history of substance use disorders.
• If you have any other risk factors for heart problems including a family history of heart disease, being overweight, being a male over 40 or a postmenopausal woman.

You should also know:

• Cafergot may sometimes cause addiction particularly in people with a substance use disorder.
• Cafergot must not be used during pregnancy as it may harm an unborn baby. Speak to your doctor about reliable forms of birth control.
• Cafergot passes into breast milk and may have undesirable effects on nursing infants.
• Do not smoke while taking this medication. Smoking while taking Cafergot may increase the risk of serious side effects including decreased blood flow to your brain and heart problems.

Common side effects of Cafergot include but are not limited to:

• Nausea, upset stomach or vomiting.
• Trouble sleeping or restlessness.
• Dizziness.

Get medical help if you have any of the following side effects of Cafergot:

• Slow, fast or irregular heartbeat.
• Cold hands or feet or numbness, tingling or a blue appearance in your fingers, toes or nails.
• Severe abdominal or stomach pain.
• Muscle pain and weakness.
• Signs of a serious problem including slurred speech, confusion, vision changes, weakness to one side of the body or pain in your chest, jaw or left arm.
• Symptoms of kidney problems including changes to your amount of urine.
• Symptoms of an allergic reaction such as difficulty breathing, hives or swelling in your face, lips or throat.

When should I take Cafergot?

Cafergot is most effective when it is taken at the first sign of a headache. It may not be as effective if taken once a headache has worsened.

How often should I take Cafergot?

Do not take more than six tablets for one headache or ten tablets during a seven-day period. If you are taking migraine medication for more than ten days each month, your headaches may actually get worse due to medication overuse headache.