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What is Estring?

Estring is a vaginal ring used to treat menopausal vaginal changes including, itching, burning, dryness, and urinary discomfort. Estring is a soft, flexible ring which releases estrogen through the vaginal wall in a stable, consistent manner for 90 days. It contains estradiol, a form of the female sex hormone estrogen.

Always follow your doctor’s instructions and use Estring exactly as prescribed.

• Wash your hands before and after inserting an Estring ring.
• Squeeze the sides of the ring and insert it as high as possible into the vagina.
• You should not be able to feel Estring once it’s inserted. If you can feel it, push it higher with a finger.
• Leave Estring in place for 90 days. If it falls out, rinse with warm water and reinsert.
• After 90 days, loop your finger through the ring and pull it out gently. Replace it with a new ring.
• Self-examine your breasts for lumps each month and have a yearly mammogram.

Estring and other estradiol medications can increase your risk of blood clots, stroke, or heart attack. Long-term use has been linked to breast, uterine, and ovarian cancer.

Do not smoke while taking Estring. This will increase your risk of blood clots, stroke and heart attack.

Before taking Estring, inform your doctor if you have any of the following:

• Liver or coronary artery disease
• Bleeding disorders
• History of stroke, heart attack, blood clots
• Hormone related cancers or breast, uterine, or cervical cancer
• Unusual vaginal bleeding

Common side effects of Estring include:

• Headache
• Nausea, vomiting, bloating, cramps
• Breast pain
• Swollen hands and feet
• Vaginal itching or discharge

Contact your doctor if you experience these more serious side effects:

• Heart attack symptoms – chest pain spreading in your jaw or shoulder, nausea, sweating
• Stroke – numbness or weakness on one side of the body, slurred speech, poor balance and coordination
• Signs of a blood clot – shortness of breath, stabbing chest pain, coughing blood, sudden vision loss, pain or warmth in legs
• Jaundice
• Breast lumps
• High blood calcium – muscle weakness, bone pain, lack of energy, increased thirst and urination, nausea, vomiting, constipation
• Swelling or tender stomach
• Unusual behavior, memory problems, confusion
• Unusual vaginal bleeding, pelvic pain

Do I need to remove Estring during intercourse?

No. Estring can remain in place and shouldn’t cause discomfort during intercourse. If it falls out, rinse with warm water and replace.

How do I dispose of Estring?

Throw in a trash that pets and children don’t have access to. Do not flush Estring down the toilet.