Zocor (simvastatin) is a statin drug prescribed to treat high cholesterol and lower the risk of heart attack and stroke in people with heart disease. Zocor slows the production of cholesterol and helps clear build-up on arterial walls (atherosclerosis) that can limit blood flow.

Always follow your doctor’s instructions and use Zocor exactly as prescribed.

• Zocor is typically taken before bed or with an evening meal.
• Follow a cholesterol-lowering diet and exercise plan.
• Your doctor will do frequent blood tests to check cholesterol levels. Do not stop taking Zocor without your doctor’s guidance.

Stop taking Zocor and tell your doctor if your become pregnant.

These drugs may increase risk of muscle problems if taken together with Zocor:

• Danazol
• Cyclosporine
• Gemfibrozil
• Nefazodone
• Antibiotics
• Antifungals
• Hepatitis C drugs
• HIV/AIDS medications

Before taking Zocor, inform your doctor if you have any of the following:

• Liver or kidney disease
• Thyroid problems
• Diabetes
• If you drink more than 2 alcoholic beverages per day

Common side effects of Zocor include:

• Headache
• Cold symptoms
• Nausea, constipation, stomach pain

Contact your doctor if you experience these more serious side effects:

• Liver symptoms – jaundice, dark urine, clay-colored stools, upper abdominal pain, weakness, fatigue, loss of appetite
• Kidney symptoms – little or no urination, swollen feet and ankles, tiredness or shortness of breath
• Unexplained muscle pain, tenderness or weakness

Can I drink alcohol while taking Zocor?

Drinking alcohol while taking Zocor can increase your risk of liver damage. Avoid alcohol, and tell your doctor if you’re used to consuming more than 2 alcoholic beverages daily.

What is a cholesterol-lowering diet?

A cholesterol-lowering diet typically involves eating fewer sources of saturated and trans fats (full-fat dairy, fatty and processed meats, packaged snacks and pastries). Eat fewer processed foods, more vegetables, and sources of fiber like whole grains and vegetables. For complete cholesterol-lowering meal plans, your doctor may recommend a consultation with a nutritionist or dietitian.